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Everything to know about Cardinals vs. Chargers tonight

The NFL heads west for a ‘Monday Night Football’ battle between the Los Angeles Chargers and Arizona Cardinals in Week 7.

The Cardinals have lost three of their last four games, and it’s been a mixed bag overall for Arizona’s offense. The middle-of-the-pack Redbird offense ranks 17th in points scored and 15th in yards. The Cardinals haven’t cracked the 15-point mark in those losses, a likely very frustrating note for Kyler Murray, who has thrown eight touchdown passes this season.

Getting their offense on track will be a tall task against the staunch Chargers defense. Los Angeles boasts the best scoring defense in football, having allowed just 66 points through five games this season. That’s the M.O. of Jim Harbaugh, whose teams have traditionally played excellent defense and ran the ball with great success.

That could also prove to be a nightmare matchup for the Cardinals defense. Arizona has had issues with stopping the run in 2024, rankings near the bottom of the NFL in rushing yards allowed and rushing TDs.

USA TODAY Sports will provide live updates, highlights and more from the Cardinals vs. Chargers Week 7 matchup below.

NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.

Cardinals vs. Chargers start time

Date: Monday, Oct. 21
Time: 9 p.m. ET | 6 p.m. PT

The Cardinals vs. Chargers matchup is the second of two ‘MNF’ games in Week 7, following the Buccaneers vs. the Ravens. It will kick off at 9 p.m. ET.

Cardinals vs. Chargers TV channel

TV channel: ESPN+ (national) | Fox 11 Plus (Los Angeles market) | Fox 10 (Phoenix market) | ESPN2 (‘ManningCast’)

ESPN+, the streaming service, is the broadcast home of ‘Monday Night Football’ in Week 7. Chris Fowler (play-by-play), Louis Riddick and Dan Orlovsky (color commentary) fill out the booth. Laura Rutledge will provide sideline reports.

ESPN’s popular alternate broadcast, the ‘ManningCast’ returns. The two former NFL quarterbacks will have double duty with both matchups on Monday.

Cardinals vs. Chargers live stream

Streaming: ESPN+

The Cardinals and Chargers matchup will not be aired on national television. The game will only be available for streaming on ESPN+. This game is the first-ever exclusive NFL game for ESPN’s streaming service.

Cardinals vs. Chargers odds, moneyline, over/under

The Chargers are favorites to defeat the Cardinals, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

Spread: Chargers (-2.5)
Moneyline: Chargers (-145); Cardinals (+120)
Over/under: 43.5

Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with Thursday Night Football odds and Monday Night Football odds.

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AFC West standings

The Chargers enter their Week 7 matchup against the Cardinals as one of three teams in the AFC West with a winning record. Here’s a look at how the division standings stack up entering “Monday Night Football”:

Chiefs (6-0)
Chargers (3-2)
Broncos (4-3)
Raiders (2-5)

NFC West standings

The Cardinals need a win in Week 7 to avoid falling to last place in the NFC West. Below is a look at the division’s pecking order ahead of “Monday Night Football.”

Seahawks (4-3)
49ers (3-4)
Cardinals (2-4)
Rams (1-4)

Cardinals vs. Chargers picks, predictions

Here’s how the USA TODAY Sports staff feels the Week 7 ‘MNF’ matchup between the Chargers and Cardinals will shape up:

Lorenzo Reyes: Chargers 29, Cardinals 13
Tyler Dragon: Chargers 23, Cardinals 21
Richard Morin: Cardinals 28, Chargers 24
Jordan Mendoza: Chargers 20, Cardinals 16

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